› 6e4v

X-ray diffraction
2Å resolution

The Crystal Structure of FhuE from E. coli in complex with its substrate Coprogen

Released:
DOI: 10.2210/pdb6e4v/pdb
PDB entry 6e4v coloured by chain, front view.
PDB entry 6e4v coloured by chain, side view.
PDB entry 6e4v coloured by chain, top view.
Source organism: Escherichia coli BW25113
Primary publication:
Determination of the molecular basis for coprogen import by Gram-negative bacteria.
Grinter R, Lithgow T
IUCrJ 6 401-411 (2019)
PMID: 31098021

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147823 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hydroxamate siderophore receptor FhuE Chain: A
Molecule details ›
Chain: A
Length: 693 amino acids
Theoretical weight: 77.47 KDa
Source organism: Escherichia coli BW25113
Expression system: Escherichia coli
UniProt:
  • Canonical: P16869 (Residues: 37-729; Coverage: 100%)
Gene names: JW1088, b1102, fhuE
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand BOG 5 x BOG
Ligand HWS 1 x HWS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 68.19Å b: 103.86Å c: 118.62Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.235
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Surveying membrane landscapes: a new look at the bacterial cell surface.
Lithgow et al. (2023)
6 other articles

4 mentions without citation

Iron Acquisition Systems of Gram-negative Bacterial Pathogens Define TonB-Dependent Pathways to Novel Antibiotics.
Klebba et al. (2021)
3 more