› 6e7o

X-ray diffraction
3Å resolution

Crystal structure of deglycosylated human EPDR1

Released:
DOI: 10.2210/pdb6e7o/pdb
PDB entry 6e7o coloured by chain, front view.
PDB entry 6e7o coloured by chain, side view.
PDB entry 6e7o coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters.
Wei Y, Xiong ZJ, Li J, Zou C, Cairo CW, Klassen JS, Privé GG
Commun Biol 2 52 (2019)
PMID: 30729188

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193955 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mammalian ependymin-related protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 194 amino acids
Theoretical weight: 22.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9UM22 (Residues: 38-224; Coverage: 100%)
Gene names: EPDR1, MERP1, UCC1
Sequence domains: Ependymin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2221
Unit cell:
a: 87.805Å b: 97.482Å c: 189.469Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.256 0.255 0.278
Expression system: Homo sapiens

Quick links

Citations

2 review citations

Updates on Genes and Genetic Mechanisms Implicated in Primary Angle-Closure Glaucoma.
Kondkar AA. (2021)
1 more