› 6eld

X-ray diffraction
2.48Å resolution

Crystal structure of TIA-1 RRM1 in complex with U1C

Released:
DOI: 10.2210/pdb6eld/pdb
PDB entry 6eld coloured by chain, front view.
PDB entry 6eld coloured by chain, side view.
PDB entry 6eld coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Jagtap PKA, Sattler M

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140601 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytotoxic granule associated RNA binding protein TIA1; U1 small nuclear ribonucleoprotein C Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 15.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P31483 (Residues: 1-92; Coverage: 24%)
  • Canonical: P09234 (Residues: 30-61; Coverage: 20%)
Gene names: SNRPC, TIA1
Sequence domains: RNA recognition motif

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P64
Unit cell:
a: 71.11Å b: 71.11Å c: 60.68Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.197 0.242
Expression system: Escherichia coli BL21

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