› 6enr

X-ray diffraction
1.84Å resolution

The ENTH domain from epsin Ent2

Released:
DOI: 10.2210/pdb6enr/pdb
PDB entry 6enr coloured by chain, front view.
PDB entry 6enr coloured by chain, side view.
PDB entry 6enr coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Epsin and Sla2 form assemblies through phospholipid interfaces.
Garcia-Alai MM, Heidemann J, Skruzny M, Gieras A, Mertens HDT, Svergun DI, Kaksonen M, Uetrecht C, Meijers R
Nat Commun 9 328 (2018)
PMID: 29362354

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170246 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epsin-2 Chain: A
Molecule details ›
Chain: A
Length: 156 amino acids
Theoretical weight: 18.43 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q05785 (Residues: 1-156; Coverage: 25%)
Gene names: ENT2, YLR206W
Sequence domains: ENTH domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: P21
Unit cell:
a: 24.395Å b: 65.726Å c: 33.735Å
α: 90° β: 97.32° γ: 90°
R-values:
R R work R free
0.168 0.165 0.222
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Novel roles of phosphoinositides in signaling, lipid transport, and disease.
Hammond et al. (2020)
2 more

1 mention without citation

Epsin and Sla2 form assemblies through phospholipid interfaces.
Garcia-Alai et al. (2018)