Function and Biology Details
Reaction catalysed:
Cleavage of peptide bonds with very broad specificity.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Nucleophile aminohydrolases, N-terminal
- Proteasome component (PCI) domain
- Proteasome, subunit alpha/beta
- Proteasome B-type subunit
- P-loop containing nucleoside triphosphate hydrolase
- Peptidase T1A, proteasome beta-subunit
- Proteasome alpha-subunit, N-terminal domain
- Proteasome beta-type subunit, conserved site
56 more domains
Structure analysis Details
Assembly composition:
hetero 32-mer (preferred)
PDBe Complex ID:
PDB-CPX-220380 (preferred)
Entry contents:
32 distinct polypeptide molecules
Macromolecules (32 distinct):
Proteasome subunit alpha type-6
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 27.43 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains:
Length: 246 amino acids
Theoretical weight: 27.43 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
P60901 (Residues: 1-246; Coverage: 100%)
Sequence domains:
Proteasome subunit alpha type-2
Molecule details ›
Chain: B
Length: 234 amino acids
Theoretical weight: 25.96 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains:
Length: 234 amino acids
Theoretical weight: 25.96 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical: P17220 (Residues: 1-234; Coverage: 100%)
Sequence domains:
Proteasome subunit alpha type-4
Proteasome subunit alpha type-7
Proteasome subunit alpha type-5
Proteasome subunit alpha type-1
Proteasome subunit alpha type-3
Proteasome subunit beta type-6
Proteasome subunit beta type-7
Proteasome subunit beta type-3
Proteasome subunit beta type-2
Proteasome subunit beta type-5
Proteasome subunit beta type-1
Proteasome subunit beta type-4
26S proteasome non-ATPase regulatory subunit 4
26S proteasome non-ATPase regulatory subunit 14
26S proteasome non-ATPase regulatory subunit 8
26S proteasome complex subunit SEM1
26S proteasome non-ATPase regulatory subunit 2
26S proteasome non-ATPase regulatory subunit 1
26S proteasome non-ATPase regulatory subunit 3
26S proteasome non-ATPase regulatory subunit 12
26S proteasome non-ATPase regulatory subunit 11
26S proteasome non-ATPase regulatory subunit 6
26S proteasome non-ATPase regulatory subunit 7
26S proteasome non-ATPase regulatory subunit 13
26S proteasome regulatory subunit 7
26S proteasome regulatory subunit 4
26S proteasome regulatory subunit 6B
26S proteasome regulatory subunit 10B
26S proteasome regulatory subunit 6A
26S proteasome regulatory subunit 8
