6ezi

X-ray diffraction
1.5Å resolution

PDZK1 domain 4 in complex with C-terminal peptide of human PepT2.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-172462 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 Chain: A
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 9.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5T2W1 (Residues: 374-460; Coverage: 17%)
Gene names: CAP70, NHERF3, PDZD1, PDZK1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Solute carrier family 15 member 2 Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q16348 (Residues: 720-729; Coverage: 1%)
Gene names: PEPT2, SLC15A2

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P6522
Unit cell:
a: 54.4Å b: 54.4Å c: 150.76Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.194 0.214
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided