› 6fb3

X-ray diffraction
2.38Å resolution

Teneurin 2 Partial Extracellular Domain

Released:
DOI: 10.2210/pdb6fb3/pdb
PDB entry 6fb3 coloured by chain, front view.
PDB entry 6fb3 coloured by chain, side view.
PDB entry 6fb3 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction.
Jackson VA, Meijer DH, Carrasquero M, van Bezouwen LS, Lowe ED, Kleanthous C, Janssen BJC, Seiradake E
Nat Commun 9 1079 (2018)
PMID: 29540701

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190109 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Ten-2, soluble form Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1859 amino acids
Theoretical weight: 208.79 KDa
Source organism: Gallus gallus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9DER5 (Residues: 955-2802; Coverage: 66%)
Gene names: ODZ2, TENM2, TNM2
Sequence domains: GHH signature containing HNH/Endo VII superfamily nuclease toxin

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 20 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 88.56Å b: 452.56Å c: 146.36Å
α: 90° β: 95.12° γ: 90°
R-values:
R R work R free
0.226 0.225 0.242
Expression system: Homo sapiens

Quick links

Citations

15 review citations

Adhesion G Protein-Coupled Receptors as Drug Targets for Neurological Diseases.
Folts et al. (2019)
14 more

10 mentions without citation

Latrophilin's Social Protein Network.
Burbach et al. (2019)
9 more