Function and Biology Details
Reaction catalysed:
ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
S-adenosylmethionine synthase isoform type-2 (preferred)
PDBe Complex ID:
PDB-CPX-151917 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
S-adenosylmethionine synthase isoform type-2
Molecule details ›
Chain: A
Length: 395 amino acids
Theoretical weight: 43.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 395 amino acids
Theoretical weight: 43.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P31153 (Residues: 1-395; Coverage: 100%)
Sequence domains:
- S-adenosylmethionine synthetase, N-terminal domain
- S-adenosylmethionine synthetase, central domain
- S-adenosylmethionine synthetase, C-terminal domain
