6fkq

X-ray diffraction
3.07Å resolution

THE CRYSTAL STRUCTURE OF A FRAGMENT OF NETRIN-1 IN COMPLEX WITH A FRAGMENT OF DRAXIN

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131962 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Netrin-1 Chain: A
Molecule details ›
Chain: A
Length: 415 amino acids
Theoretical weight: 46.83 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O95631 (Residues: 39-453; Coverage: 72%)
Gene names: NTN1, NTN1L
Sequence domains:
Structure domains: Galactose-binding domain-like
Draxin Chain: B
Molecule details ›
Chain: B
Length: 19 amino acids
Theoretical weight: 2.3 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8NBI3 (Residues: 225-243; Coverage: 6%)
Gene names: C1orf187, DRAXIN, PSEC0258, UNQ3119/PRO10268

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: P6422
Unit cell:
a: 130.794Å b: 130.794Å c: 183.87Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.237 0.235 0.271
Expression system: Homo sapiens