6fp4

X-ray diffraction
2.5Å resolution

Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1,8-Naphthyridine-2-carboxylic acid

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-166728 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin glutathione reductase Chain: A
Molecule details ›
Chain: A
Length: 598 amino acids
Theoretical weight: 65.11 KDa
Source organism: Schistosoma mansoni
Expression system: Escherichia coli BL21(DE3)
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: C2
Unit cell:
a: 142.316Å b: 101.584Å c: 58.783Å
α: 90° β: 112.78° γ: 90°
R-values:
R R work R free
0.197 0.195 0.229
Expression system: Escherichia coli BL21(DE3)