› 6fxb

X-ray diffraction
2Å resolution

Bovine beta-lactoglobulin variant A at pH 4.0

Released:
DOI: 10.2210/pdb6fxb/pdb
PDB entry 6fxb coloured by chain, front view.
PDB entry 6fxb coloured by chain, side view.
PDB entry 6fxb coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Revealing the Dimeric Crystal and Solution Structure of β-Lactoglobulin at pH 4 and Its pH and Salt Dependent Monomer-Dimer Equilibrium.
Khan S, Ipsen R, Almdal K, Svensson B, Harris P
Biomacromolecules 19 2905-2912 (2018)
PMID: 29737841

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136154 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-lactoglobulin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 162 amino acids
Theoretical weight: 18.39 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02754 (Residues: 17-178; Coverage: 100%)
Gene name: LGB
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand NO3 2 x NO3
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Unit cell:
a: 67.11Å b: 75.61Å c: 140.62Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.232 0.27

Quick links

Citations

1 review citation

β-Lactoglobulin and Glycodelin: Two Sides of the Same Coin?
Sawyer L. (2021)
8 other articles

1 mention without citation

Electrostatics in Computational Biophysics and Its Implications for Disease Effects.
Sun et al. (2022)