PDB 6fyy structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

GTP + H(2)O = GDP + phosphate

Biochemical function:

structural constituent of ribosome

Biological process:

translation

Cellular component:

ribosome

Sequence domains:

157 more domains

Structure analysis Details

Assembly composition:

hetero 47-mer (preferred)

Assembly name:

Eukaryotic translation initiation factor 2 complex and RNA (preferred)

PDBe Complex ID:

PDB-CPX-108171 (preferred)

Entry contents:

44 distinct polypeptide molecules
3 distinct RNA molecules

Macromolecules (47 distinct):

Small ribosomal subunit protein uS2 Chain: A

Molecule details ›

Chain: A
Length: 254 amino acids
Theoretical weight: 28.26 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CN12 (Residues: 1-254; Coverage: 100%)

Gene names: KLLA0E16171g, RPS0
Sequence domains: Ribosomal protein S2

Small ribosomal subunit protein eS1 Chain: B

Molecule details ›

Chain: B
Length: 255 amino acids
Theoretical weight: 29.01 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CWD0 (Residues: 1-255; Coverage: 100%)

Gene names: KLLA0B05060g, RPS1
Sequence domains: Ribosomal S3Ae family

S5 DRBM domain-containing protein Chain: C

Molecule details ›

Chain: C
Length: 259 amino acids
Theoretical weight: 27.65 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CKL3 (Residues: 1-259; Coverage: 100%)

Gene name: KLLA0_F09812g
Sequence domains:

40S ribosomal protein S3 Chain: D

Molecule details ›

Chain: D
Length: 237 amino acids
Theoretical weight: 26.3 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CRK7 (Residues: 1-237; Coverage: 100%)

Gene name: KLLA0_D08305g
Sequence domains:

40S ribosomal protein S4 Chain: E

Molecule details ›

Chain: E
Length: 261 amino acids
Theoretical weight: 29.62 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CWJ2 (Residues: 1-261; Coverage: 100%)

Gene name: KLLA0_B03652g
Sequence domains:

Small ribosomal subunit protein uS7 domain-containing protein Chain: F

Molecule details ›

Chain: F
Length: 227 amino acids
Theoretical weight: 25.39 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CRA3 (Residues: 1-227; Coverage: 100%)

Gene name: KLLA0_D10659g
Sequence domains: Ribosomal protein S7p/S5e

Small ribosomal subunit protein eS6 Chain: G

Molecule details ›

Chain: G
Length: 236 amino acids
Theoretical weight: 26.97 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CM04 (Residues: 1-236; Coverage: 100%)

Gene names: KLLA0E24090g, RPS6
Sequence domains: Ribosomal protein S6e

40S ribosomal protein S7 Chain: H

Molecule details ›

Chain: H
Length: 190 amino acids
Theoretical weight: 21.74 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CTD6 (Residues: 1-190; Coverage: 100%)

Gene name: KLLA0_C13519g
Sequence domains: Ribosomal protein S7e

40S ribosomal protein S8 Chain: I

Molecule details ›

Chain: I
Length: 201 amino acids
Theoretical weight: 22.64 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CMG3 (Residues: 1-201; Coverage: 100%)

Gene name: KLLA0_E20461g
Sequence domains: Ribosomal protein S8e

KLLA0E23673p Chain: J

Molecule details ›

Chain: J
Length: 188 amino acids
Theoretical weight: 21.59 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CM18 (Residues: 1-188; Coverage: 100%)

Gene name: KLLA0_E23673g
Sequence domains:

Plectin/eS10 N-terminal domain-containing protein Chain: K

Molecule details ›

Chain: K
Length: 106 amino acids
Theoretical weight: 12.58 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CVZ5 (Residues: 1-106; Coverage: 100%)

Gene name: KLLA0_B08173g
Sequence domains: Plectin/S10 domain

Small ribosomal subunit protein uS17 N-terminal domain-containing protein Chain: L

Molecule details ›

Chain: L
Length: 156 amino acids
Theoretical weight: 17.84 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CX80 (Residues: 1-156; Coverage: 100%)

Gene name: KLLA0_A10483g
Sequence domains:

40S ribosomal protein S12 Chain: M

Molecule details ›

Chain: M
Length: 134 amino acids
Theoretical weight: 14.47 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CLU4 (Residues: 1-134; Coverage: 100%)

Gene name: KLLA0_F00352g
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

Small ribosomal subunit protein uS15 N-terminal domain-containing protein Chain: N

Molecule details ›

Chain: N
Length: 151 amino acids
Theoretical weight: 16.99 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CJK0 (Residues: 1-151; Coverage: 100%)

Gene name: KLLA0_F18040g
Sequence domains:

Small ribosomal subunit protein uS11 Chain: O

Molecule details ›

Chain: O
Length: 137 amino acids
Theoretical weight: 14.53 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: P27069 (Residues: 1-137; Coverage: 100%)

Gene names: CRY1, KLLA0B07623g, RPS14
Sequence domains: Ribosomal protein S11

Rps15 Chain: P

Molecule details ›

Chain: P
Length: 142 amino acids
Theoretical weight: 15.99 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CKV4 (Residues: 1-142; Coverage: 100%)

Gene name: KLLA0_F07843g
Sequence domains: Ribosomal protein S19

Small ribosomal subunit protein uS9 Chain: Q

Molecule details ›

Chain: Q
Length: 143 amino acids
Theoretical weight: 15.87 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q875N2 (Residues: 1-143; Coverage: 100%)

Gene names: KLLA0E22077g, RPS16
Sequence domains: Ribosomal protein S9/S16

KLLA0B01474p Chain: R

Molecule details ›

Chain: R
Length: 136 amino acids
Theoretical weight: 15.72 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CWU3 (Residues: 1-136; Coverage: 100%)

Gene name: KLLA0_B01474g
Sequence domains: Ribosomal S17

KLLA0B01562p Chain: S

Molecule details ›

Chain: S
Length: 146 amino acids
Theoretical weight: 17.08 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CWT9 (Residues: 1-146; Coverage: 100%)

Gene name: KLLA0_B01562g
Sequence domains: Ribosomal protein S13/S18

KLLA0A07194p Chain: T

Molecule details ›

Chain: T
Length: 144 amino acids
Theoretical weight: 15.88 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CXM0 (Residues: 1-144; Coverage: 100%)

Gene name: KLLA0_A07194g
Sequence domains: Ribosomal protein S19e

Small ribosomal subunit protein uS10 domain-containing protein Chain: U

Molecule details ›

Chain: U
Length: 117 amino acids
Theoretical weight: 13.34 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CIM1 (Residues: 1-117; Coverage: 100%)

Gene name: KLLA0_F25542g
Sequence domains: Ribosomal protein S10p/S20e

Small ribosomal subunit protein eS21 Chain: V

Molecule details ›

Chain: V
Length: 87 amino acids
Theoretical weight: 9.8 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CXT6 (Residues: 1-87; Coverage: 100%)

Gene names: KLLA0A05700g, RPS21
Sequence domains: Ribosomal protein S21e

Small ribosomal subunit protein uS8 Chain: W

Molecule details ›

Chain: W
Length: 130 amino acids
Theoretical weight: 14.65 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CW21 (Residues: 1-130; Coverage: 100%)

Gene names: KLLA0B07601g, RPS22
Sequence domains: Ribosomal protein S8

40S ribosomal protein S23 Chain: X

Molecule details ›

Chain: X
Length: 145 amino acids
Theoretical weight: 16.05 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: F2Z602 (Residues: 1-145; Coverage: 100%)

Gene name: KLLA0_B11231g
Sequence domains: Ribosomal protein S12/S23

40S ribosomal protein S24 Chain: Y

Molecule details ›

Chain: Y
Length: 135 amino acids
Theoretical weight: 15.19 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CU44 (Residues: 1-135; Coverage: 100%)

Gene name: KLLA0_C07755g
Sequence domains: Ribosomal protein S24e

40S ribosomal protein S25 Chain: Z

Molecule details ›

Chain: Z
Length: 108 amino acids
Theoretical weight: 12 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CW78 (Residues: 1-108; Coverage: 100%)

Gene name: KLLA0_B06182g
Sequence domains: S25 ribosomal protein

40S ribosomal protein S26 Chain: a

Molecule details ›

Chain: a
Length: 119 amino acids
Theoretical weight: 13.54 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CS01 (Residues: 1-119; Coverage: 100%)

Gene name: KLLA0_D05115g
Sequence domains: Ribosomal protein S26e

40S ribosomal protein S27 Chain: b

Molecule details ›

Chain: b
Length: 82 amino acids
Theoretical weight: 8.88 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CNL2 (Residues: 1-82; Coverage: 100%)

Gene name: KLLA0_E11661g
Sequence domains: Ribosomal protein S27

Small ribosomal subunit protein eS28 Chain: c

Molecule details ›

Chain: c
Length: 67 amino acids
Theoretical weight: 7.55 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: P33285 (Residues: 1-67; Coverage: 100%)

Gene names: KLLA0F20383g, RPS28
Sequence domains: Ribosomal protein S28e

Small ribosomal subunit protein uS14 Chain: d

Molecule details ›

Chain: d
Length: 56 amino acids
Theoretical weight: 6.66 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CPG3 (Residues: 1-56; Coverage: 100%)

Gene names: KLLA0E05071g, RPS29
Sequence domains: Ribosomal protein S14p/S29e

40S ribosomal protein S30 Chain: e

Molecule details ›

Chain: e
Length: 63 amino acids
Theoretical weight: 7.14 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CUH5 (Residues: 1-63; Coverage: 100%)

Gene name: KLLA0_C04809g
Sequence domains: Ribosomal protein S30

Ubiquitin-ribosomal protein eS31 fusion protein Chain: f

Molecule details ›

Chain: f
Length: 150 amino acids
Theoretical weight: 17.11 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: P69061 (Residues: 1-150; Coverage: 100%)

Gene names: KLLA0D18304g, ubi3
Sequence domains:

Asc1 Chain: g

Molecule details ›

Chain: g
Length: 326 amino acids
Theoretical weight: 35.83 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: Q6CNI7 (Residues: 1-326; Coverage: 100%)

Gene name: KLLA0_E12277g
Sequence domains: WD domain, G-beta repeat

Small ribosomal subunit protein eS32A Chain: h

Molecule details ›

Chain: h
Length: 25 amino acids
Theoretical weight: 3.35 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:

Canonical: P0CX86 (Residues: 1-25; Coverage: 100%)

Gene names: D1290, RPL41A, RPL47A, YDL184C, YL41A
Sequence domains: Ribosomal protein L41

Eukaryotic translation initiation factor 1A Chain: i

Molecule details ›

Chain: i
Length: 153 amino acids
Theoretical weight: 17.46 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:

Canonical: P38912 (Residues: 1-153; Coverage: 100%)

Gene names: TIF11, YM8156.02C, YMR260C
Sequence domains: Translation initiation factor 1A / IF-1

Eukaryotic translation initiation factor 2 subunit alpha Chain: j

Molecule details ›

Chain: j
Length: 304 amino acids
Theoretical weight: 34.76 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P20459 (Residues: 1-304; Coverage: 100%)

Gene names: J1429, SUI2, TIF211, YJR007W
Sequence domains:

Eukaryotic translation initiation factor 2 subunit gamma Chain: k

Molecule details ›

Chain: k
Length: 527 amino acids
Theoretical weight: 57.94 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P32481 (Residues: 1-527; Coverage: 100%)

Gene names: GCD11, SUI4, TIF213, YER025W
Sequence domains:

Eukaryotic translation initiation factor 2 subunit beta Chain: l

Molecule details ›

Chain: l
Length: 285 amino acids
Theoretical weight: 31.63 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P09064 (Residues: 1-285; Coverage: 100%)

Gene names: SUI3, TIF212, YPL237W
Sequence domains: Domain found in IF2B/IF5

Eukaryotic translation initiation factor 5 Chain: m

Molecule details ›

Chain: m
Length: 405 amino acids
Theoretical weight: 45.32 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:

Canonical: P38431 (Residues: 1-405; Coverage: 100%)

Gene names: TIF5, YP3085.05, YPR041W
Sequence domains:

Eukaryotic translation initiation factor 3 subunit A Chain: o

Molecule details ›

Chain: o
Length: 964 amino acids
Theoretical weight: 110.52 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P38249 (Residues: 1-964; Coverage: 100%)

Gene names: RPG1, TIF32, YBR0734, YBR079C

Eukaryotic translation initiation factor 3 subunit B Chain: p

Molecule details ›

Chain: p
Length: 763 amino acids
Theoretical weight: 88.24 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P06103 (Residues: 1-763; Coverage: 100%)

Gene names: CDC63, PRT1, YOR361C
Sequence domains:

Eukaryotic translation initiation factor 3 subunit C Chain: q

Molecule details ›

Chain: q
Length: 812 amino acids
Theoretical weight: 86.54 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P32497 (Residues: 251-812; Coverage: 69%)

Gene names: NIP1, YM9924.01C, YM9952.11C, YMR309C
Sequence domains:

Eukaryotic translation initiation factor 3 subunit G Chain: r

Molecule details ›

Chain: r
Length: 274 amino acids
Theoretical weight: 30.52 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: A6ZZ25 (Residues: 1-274; Coverage: 100%)

Gene names: SCY_1313, TIF35
Sequence domains:

Eukaryotic translation initiation factor 3 subunit I Chain: s

Molecule details ›

Chain: s
Length: 347 amino acids
Theoretical weight: 38.8 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt: