› 6g52

X-ray diffraction
3.69Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180113 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metal transporter CNNM4 Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 189 amino acids
Theoretical weight: 21.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6P4Q7 (Residues: 545-730; Coverage: 24%)
Gene names: ACDP4, CNNM4, KIAA1592

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 36 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3221
Unit cell:
a: 116.738Å b: 116.738Å c: 243.459Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.286 0.284 0.303
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Structural and functional comparison of magnesium transporters throughout evolution.
Franken et al. (2022)
8 other articles

2 mentions without citation

The phenotypic and genetic spectrum of patients with heterozygous mutations in cyclin M2 (CNNM2).
Franken et al. (2021)
1 more