6g57

X-ray diffraction
2.8Å resolution

Structure of the H1 domain of human KCTD8

Released:
Source organism: Homo sapiens
Entry authors: Pinkas DM, Bufton JC, Strain-Damerell CM, Fairhead M, Burgess-Brown NA, von Delft F, Arrowsmith CH, Edwards AM, Bountra C, Bullock AN

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-180609 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BTB/POZ domain-containing protein KCTD8 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 124 amino acids
Theoretical weight: 14.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6ZWB6 (Residues: 201-322; Coverage: 26%)
Gene name: KCTD8

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P6122
Unit cell:
a: 92.117Å b: 92.117Å c: 219.355Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.296 0.295 0.342
Expression system: Escherichia coli BL21(DE3)