Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-140667 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Molecule details ›
Chain: B
Length: 339 amino acids
Theoretical weight: 37.29 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Length: 339 amino acids
Theoretical weight: 37.29 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P62873 (Residues: 2-340; Coverage: 100%)
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Molecule details ›
Chain: G
Length: 71 amino acids
Theoretical weight: 7.85 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: GGL domain
Structure domains: Transducin (heterotrimeric G protein), gamma chain
Length: 71 amino acids
Theoretical weight: 7.85 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P59768 (Residues: 1-71; Coverage: 100%)
Sequence domains: GGL domain
Structure domains: Transducin (heterotrimeric G protein), gamma chain
Guanine nucleotide-binding protein G(o) subunit alpha
Molecule details ›
Chain: A
Length: 225 amino acids
Theoretical weight: 25.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: G-protein alpha subunit
Length: 225 amino acids
Theoretical weight: 25.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P09471 (Residues: 4-57, 182-354; Coverage: 61%)
Sequence domains: G-protein alpha subunit
5-hydroxytryptamine receptor 1B
Molecule details ›
Chain: S
Length: 364 amino acids
Theoretical weight: 41.27 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: 7 transmembrane receptor (rhodopsin family)
Length: 364 amino acids
Theoretical weight: 41.27 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P28222 (Residues: 34-390; Coverage: 92%)
Sequence domains: 7 transmembrane receptor (rhodopsin family)
