› 6g9z

X-ray diffraction
1.43Å resolution

Crystal structure of human histidine triad nucleotide-binding protein 1 (hHINT1) crystallized at P212121 space group, with visible extended fragment of N-terminus

Released:
DOI: 10.2210/pdb6g9z/pdb
PDB entry 6g9z coloured by chain, front view.
PDB entry 6g9z coloured by chain, side view.
PDB entry 6g9z coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dolot RM, Seda A, Nawrot BC

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156024 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine 5'-monophosphoramidase HINT1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 126 amino acids
Theoretical weight: 13.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P49773 (Residues: 1-126; Coverage: 100%)
Gene names: HINT, HINT1, PKCI1, PRKCNH1
Sequence domains: HIT domain
Structure domains: HIT-like

Ligands and Environments

1 bound ligand:
Ligand LMR 1 x LMR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 46.075Å b: 63.379Å c: 76.836Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.224 0.277
Expression system: Escherichia coli BL21

Quick links