› 6gcb

X-ray diffraction
1.8Å resolution

Crystal structure of glutathione transferase Xi 3 from Trametes versicolor in complex with glutathione

Released:
DOI: 10.2210/pdb6gcb/pdb
PDB entry 6gcb coloured by chain, front view.
PDB entry 6gcb coloured by chain, side view.
PDB entry 6gcb coloured by chain, top view.
Source organism: Trametes versicolor
Primary publication:
Trametes versicolor glutathione transferase Xi 3, a dual Cys-GST with catalytic specificities of both Xi and Omega classes.
Schwartz M, Perrot T, Deroy A, Roret T, Morel-Rouhier M, Mulliert G, Gelhaye E, Favier F, Didierjean C
FEBS Lett 592 3163-3172 (2018)
PMID: 30112765

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104859 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GST C-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 325 amino acids
Theoretical weight: 37.16 KDa
Source organism: Trametes versicolor
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A3F2YM27 (Residues: 1-325; Coverage: 100%)
Sequence domains:

Ligands and Environments


Cofactor: Ligand GSH 2 x GSH
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P43212
Unit cell:
a: 72.37Å b: 72.37Å c: 316.71Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.161 0.189
Expression system: Escherichia coli

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Citations

2 citation in other articles

Characterization of Xi-class mycothiol S-transferase from Corynebacterium glutamicum and its protective effects in oxidative stress.
Si et al. (2019)
1 more