› 6geu

X-ray diffraction
1.55Å resolution

Crystal structure of the C230A mutant of human IBA57

Released:
DOI: 10.2210/pdb6geu/pdb
PDB entry 6geu coloured by chain, front view.
PDB entry 6geu coloured by chain, side view.
PDB entry 6geu coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
IBA57 Recruits ISCA2 to Form a [2Fe-2S] Cluster-Mediated Complex.
Gourdoupis S, Nasta V, Calderone V, Ciofi-Baffoni S, Banci L
J Am Chem Soc 140 14401-14412 (2018)
PMID: 30269484

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178301 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative transferase CAF17, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 314 amino acids
Theoretical weight: 33.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5T440 (Residues: 43-356; Coverage: 88%)
Gene names: C1orf69, IBA57

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P1
Unit cell:
a: 38.36Å b: 43.06Å c: 58.25Å
α: 76.27° β: 76.17° γ: 70.94°
R-values:
R R work R free
0.162 0.16 0.203
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis.
Maio et al. (2020)
8 more