› 6gnx

X-ray diffraction
2.9Å resolution

Crystal structure of the MAJIN-TERB2 heterotetrameric complex - selenomethionine derivative

Released:
DOI: 10.2210/pdb6gnx/pdb
PDB entry 6gnx coloured by chain, front view.
PDB entry 6gnx coloured by chain, side view.
PDB entry 6gnx coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1.
Dunce JM, Milburn AE, Gurusaran M, da Cruz I, Sen LT, Benavente R, Davies OR
Nat Commun 9 5355 (2018)
PMID: 30559341

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174715 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Membrane-anchored junction protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 114 amino acids
Theoretical weight: 13.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3KP22 (Residues: 1-49; Coverage: 28%)
Gene names: C11orf85, MAJIN
Sequence domains: Membrane-anchored junction protein
Telomere repeats-binding bouquet formation protein 2 Chains: B, D
Molecule details ›
Chains: B, D
Length: 55 amino acids
Theoretical weight: 6.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NHR7 (Residues: 169-220; Coverage: 24%)
Gene names: C15orf43, TERB2

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P3221
Unit cell:
a: 59.88Å b: 59.88Å c: 159.93Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.259 0.254 0.304
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Crossover Interference: Shedding Light on the Evolution of Recombination.
Otto et al. (2019)
2 more

5 mentions without citation

Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1.
Dunce et al. (2018)
4 more