› 6gqe

X-ray diffraction
2.15Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101037 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RRM domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 18.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0B8RZH0 (Residues: 192-355; Coverage: 28%)
Gene name: IGF2BP3
Sequence domains: KH domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 36.2Å b: 58.09Å c: 60.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.233 0.293
Expression system: Escherichia coli

Quick links

Citations

8 review citations

IGF2BP3 From Physiology to Cancer: Novel Discoveries, Unsolved Issues, and Future Perspectives.
Mancarella et al. (2019)
7 more

3 mentions without citation

Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3.
Schneider et al. (2019)
2 more