› 6gup

X-ray diffraction
1.85Å resolution

Siderophore hydrolase EstB from Aspergillus fumigatus

Released:
DOI: 10.2210/pdb6gup/pdb
PDB entry 6gup coloured by chain, front view.
PDB entry 6gup coloured by chain, side view.
PDB entry 6gup coloured by chain, top view.
Source organism: Aspergillus fumigatus
Primary publication:
Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases.
Ecker F, Haas H, Groll M, Huber EM
Angew Chem Int Ed Engl 57 14624-14629 (2018)
PMID: 30070018

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175816 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fusarinine C esterase sidJ Chains: A, B
Molecule details ›
Chains: A, B
Length: 355 amino acids
Theoretical weight: 39.02 KDa
Source organism: Aspergillus fumigatus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4WF56 (Residues: 2-354; Coverage: 100%)
Gene names: AFUA_3G03390, sidJ
Sequence domains: Protein of unknown function (DUF1749)

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 48.93Å b: 102.85Å c: 65.06Å
α: 90° β: 92.14° γ: 90°
R-values:
R R work R free
0.213 0.211 0.243
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Siderophore-Based Molecular Imaging of Fungal and Bacterial Infections-Current Status and Future Perspectives.
Petrik et al. (2020)
4 other articles