› 6gw5

X-ray diffraction
2.52Å resolution

X-ray structure of the Helicobacter pylori SabA adhesin domain

Released:
DOI: 10.2210/pdb6gw5/pdb
PDB entry 6gw5 coloured by chain, front view.
PDB entry 6gw5 coloured by chain, side view.
PDB entry 6gw5 coloured by chain, top view.
Source organism: Helicobacter pylori
Primary publication:
Hop-family Helicobacter outer membrane adhesins form a novel class of Type 5-like secretion proteins with an interrupted β-barrel domain.
Coppens F, Castaldo G, Debraekeleer A, Subedi S, Moonens K, Lo A, Remaut H
Mol Microbiol 110 33-46 (2018)
PMID: 29995350

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195670 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 440 amino acids
Theoretical weight: 48.67 KDa
Source organism: Helicobacter pylori
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9ZLB8 (Residues: 42-475; Coverage: 69%)
Gene name: jhp_0662

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Unit cell:
a: 69.146Å b: 87.321Å c: 169.007Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.202 0.256
Expression system: Escherichia coli BL21

Quick links

Citations

6 review citations

Type V Secretion Systems: An Overview of Passenger Domain Functions.
Meuskens et al. (2019)
5 more

1 mention without citation

Structural and binding characterization of the LacdiNAc-specific adhesin (LabA; HopD) exodomain from Helicobacter pylori.
Paraskevopoulou et al. (2021)