Function and Biology Details
Reaction catalysed:
L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-172061 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
EKC/KEOPS complex subunit LAGE3
Molecule details ›
Chain: B
Length: 143 amino acids
Theoretical weight: 14.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Transcription factor Pcc1
Length: 143 amino acids
Theoretical weight: 14.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q14657 (Residues: 1-143; Coverage: 100%)
Sequence domains: Transcription factor Pcc1
EKC/KEOPS complex subunit GON7
Molecule details ›
Chain: D
Length: 106 amino acids
Theoretical weight: 11.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Domain of unknown function (DUF4611)
Length: 106 amino acids
Theoretical weight: 11.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9BXV9 (Residues: 1-100; Coverage: 100%)
Sequence domains: Domain of unknown function (DUF4611)
tRNA N6-adenosine threonylcarbamoyltransferase
Molecule details ›
Chain: K
Length: 335 amino acids
Theoretical weight: 36.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: tRNA N6-adenosine threonylcarbamoyltransferase
Length: 335 amino acids
Theoretical weight: 36.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9NPF4 (Residues: 1-335; Coverage: 100%)
Sequence domains: tRNA N6-adenosine threonylcarbamoyltransferase
