Function and Biology Details
Reactions catalysed:
Hypoxia-inducible factor-L-asparagine + 2-oxoglutarate + O(2) = hypoxia-inducible factor-(3S)-3-hydroxy-L-asparagine + succinate + CO(2)
[Ankyrin-repeat domain protein]-L-asparagine + 2-oxoglutarate + O(2) = [ankyrin-repeat domain protein]-(3S)-3-hydroxy-L-asparagine + succinate + CO(2)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185514 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hypoxia-inducible factor 1-alpha inhibitor
Molecule details ›
Chain: A
Length: 349 amino acids
Theoretical weight: 40.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Cupin-like domain
Length: 349 amino acids
Theoretical weight: 40.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9NWT6 (Residues: 1-349; Coverage: 100%)
Sequence domains: Cupin-like domain
Transient receptor potential cation channel subfamily V member 3
Molecule details ›
Chain: D
Length: 27 amino acids
Theoretical weight: 2.78 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 27 amino acids
Theoretical weight: 2.78 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q8NET8 (Residues: 220-246; Coverage: 3%)
