› 6he4

Electron Microscopy
4.85Å resolution

AAA-ATPase ring of PAN-proteasomes

Released:
DOI: 10.2210/pdb6he4/pdb
PDB entry 6he4 coloured by chain, front view.
PDB entry 6he4 coloured by chain, side view.
PDB entry 6he4 coloured by chain, top view.
Source organism: Archaeoglobus fulgidus DSM 4304
Primary publication:
Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle.
Majumder P, Rudack T, Beck F, Danev R, Pfeifer G, Nagy I, Baumeister W
Proc Natl Acad Sci U S A 116 534-539 (2019)
PMID: 30559193
Related structures: EMD-0209

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128007 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteasome-activating nucleotidase Chains: H, I, J, K, L, M
Molecule details ›
Chains: H, I, J, K, L, M
Length: 267 amino acids
Theoretical weight: 29.74 KDa
Source organism: Archaeoglobus fulgidus DSM 4304
Expression system: Escherichia coli
UniProt:
  • Canonical: O28303 (Residues: 123-389; Coverage: 67%)
Gene names: AF_1976, pan
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand ATP 4 x ATP
Ligand MG 5 x MG
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.85Å
Relevant EMDB volumes: EMD-0209
Expression system: Escherichia coli

Quick links

Citations

11 review citations

The molecular principles governing the activity and functional diversity of AAA+ proteins.
Puchades et al. (2020)
10 more

1 mention without citation

Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle.
Majumder et al. (2019)