› 6hj4

X-ray diffraction
2.43Å resolution

Crystal structure of Whitewater Arroyo virus GP1 glycoprotein at pH 7.5

Released:
DOI: 10.2210/pdb6hj4/pdb
PDB entry 6hj4 coloured by chain, front view.
PDB entry 6hj4 coloured by chain, side view.
PDB entry 6hj4 coloured by chain, top view.
Source organism: Whitewater Arroyo mammarenavirus
Primary publication:
Structure-Based Classification Defines the Discrete Conformational Classes Adopted by the Arenaviral GP1.
Pryce R, Ng WM, Zeltina A, Watanabe Y, El Omari K, Wagner A, Bowden TA
J Virol 93 (2019)
PMID: 30305351

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187480 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycoprotein G1 Chain: A
Molecule details ›
Chain: A
Length: 165 amino acids
Theoretical weight: 18.65 KDa
Source organism: Whitewater Arroyo mammarenavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q911P0 (Residues: 74-226; Coverage: 32%)
Gene names: GP-C, GPC
Sequence domains: Arenavirus glycoprotein

Ligands and Environments

2 bound ligands:
Ligand NAG 3 x NAG
Ligand CD 5 x CD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04, DIAMOND BEAMLINE I23
Spacegroup: P6322
Unit cell:
a: 106.66Å b: 106.66Å c: 74.81Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.222 0.22 0.252
Expression system: Homo sapiens

Quick links

Citations

2 review citations

Recent Advances in Bunyavirus Glycoprotein Research: Precursor Processing, Receptor Binding and Structure.
Hulswit et al. (2021)
1 more

1 mention without citation

Structure-Based Classification Defines the Discrete Conformational Classes Adopted by the Arenaviral GP1.
Pryce et al. (2019)