› 6hwi

Electron Microscopy
7.2Å resolution

Immature M-PMV capsid hexamer structure in intact virus particles

Released:
DOI: 10.2210/pdb6hwi/pdb
PDB entry 6hwi coloured by chain, front view.
PDB entry 6hwi coloured by chain, side view.
PDB entry 6hwi coloured by chain, top view.
Source organism: Mason-Pfizer monkey virus
Primary publication:
Structure and architecture of immature and mature murine leukemia virus capsids.
Qu K, Glass B, Doležal M, Schur FKM, Murciano B, Rein A, Rumlová M, Ruml T, Kräusslich HG, Briggs JAG
Proc Natl Acad Sci U S A 115 E11751-E11760 (2018)
PMID: 30478053
Related structures: EMD-0290

Function and Biology Details

Reaction catalysed: 
dUTP + H(2)O = dUMP + diphosphate
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo octadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139634 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein p27 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 200 amino acids
Theoretical weight: 21.82 KDa
Source organism: Mason-Pfizer monkey virus
Expression system: Homo sapiens
UniProt:
  • Canonical: P07570 (Residues: 317-516; Coverage: 22%)
Gene name: gag-pro
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 7.2Å
Relevant EMDB volumes: EMD-0290
Expression system: Homo sapiens

Quick links

Citations

9 review citations

Maturation of retroviruses.
Pornillos et al. (2019)
8 more

4 mentions without citation

Molecular architecture and conservation of an immature human endogenous retrovirus.
Krebs et al. (2023)
3 more