› 6i7o

Electron Microscopy
5.3Å resolution

The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition.

Released:
DOI: 10.2210/pdb6i7o/pdb
PDB entry 6i7o coloured by chain, front view.
PDB entry 6i7o coloured by chain, side view.
PDB entry 6i7o coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
Ikeuchi K, Tesina P, Matsuo Y, Sugiyama T, Cheng J, Saeki Y, Tanaka K, Becker T, Beckmann R, Inada T
EMBO J 38 (2019)
PMID: 30609991
Related structures: EMD-4427

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 163-mer (preferred)
PDBe Complex ID:
PDB-CPX-126882 (preferred)
Entry contents:
75 distinct polypeptide molecules
9 distinct RNA molecules
Macromolecules (84 distinct):
Large ribosomal subunit protein uL2A Chains: AW, XW
Molecule details ›
Chains: AW, XW
Length: 252 amino acids
Theoretical weight: 27.22 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX45 (Residues: 2-253; Coverage: 99%)
Gene names: RPL2A, RPL5B, YFR031BC, YFR031C-A
Sequence domains:
Large ribosomal subunit protein uL3 Chains: BA, YA
Molecule details ›
Chains: BA, YA
Length: 386 amino acids
Theoretical weight: 43.72 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P14126 (Residues: 2-387; Coverage: 100%)
Gene names: MAK8, RPL3, TCM1, YOR063W, YOR29-14
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4A Chains: BE, YE
Molecule details ›
Chains: BE, YE
Length: 361 amino acids
Theoretical weight: 39.03 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P10664 (Residues: 2-362; Coverage: 100%)
Gene names: RPL2, RPL2A, RPL4A, YBR0315, YBR031W
Sequence domains:
Large ribosomal subunit protein uL18 Chains: BI, YI
Molecule details ›
Chains: BI, YI
Length: 294 amino acids
Theoretical weight: 33.42 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P26321 (Residues: 4-297; Coverage: 99%)
Gene names: LPI14W, RPL1, RPL1A, RPL5, YPL131W
Sequence domains:
Large ribosomal subunit protein eL6A Chains: BM, YM
Molecule details ›
Chains: BM, YM
Length: 176 amino acids
Theoretical weight: 20 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q02326 (Residues: 1-176; Coverage: 100%)
Gene names: RPL17A, RPL6A, YL16A, YML073C
Sequence domains: Ribosomal protein L6e
Large ribosomal subunit protein uL30A Chains: BO, YO
Molecule details ›
Chains: BO, YO
Length: 223 amino acids
Theoretical weight: 25.34 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05737 (Residues: 22-244; Coverage: 91%)
Gene names: RPL6A, RPL7A, RPL8A, YGL076C, YL8A
Sequence domains:
Large ribosomal subunit protein eL8A Chains: AA, XA
Molecule details ›
Chains: AA, XA
Length: 231 amino acids
Theoretical weight: 25.66 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P17076 (Residues: 24-254; Coverage: 90%)
Gene names: MAK7, RPL4A, RPL8A, YHL033C
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein uL6A Chains: AD, XD
Molecule details ›
Chains: AD, XD
Length: 190 amino acids
Theoretical weight: 21.49 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05738 (Residues: 1-190; Coverage: 100%)
Gene names: RPL8A, RPL9, RPL9A, YGL147C
Sequence domains: Ribosomal protein L6
Large ribosomal subunit protein uL16 Chains: BD, YD
Molecule details ›
Chains: BD, YD
Length: 221 amino acids
Theoretical weight: 25.41 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P41805 (Residues: 1-221; Coverage: 100%)
Gene names: GRC5, QSR1, RPL10, YLR075W
Sequence domains: Ribosomal protein L16p/L10e
Large ribosomal subunit protein uL5B Chains: AG, XG
Molecule details ›
Chains: AG, XG
Length: 169 amino acids
Theoretical weight: 19.27 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q3E757 (Residues: 6-174; Coverage: 97%)
Gene names: RP39B, RPL11B, RPL16B, YGR085C
Sequence domains:
Large ribosomal subunit protein eL13A Chains: AJ, XJ
Molecule details ›
Chains: AJ, XJ
Length: 194 amino acids
Theoretical weight: 21.96 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q12690 (Residues: 2-195; Coverage: 98%)
Gene names: RPL13A, YDL082W
Sequence domains: Ribosomal protein L13e
Large ribosomal subunit protein eL14A Chains: AM, XM
Molecule details ›
Chains: AM, XM
Length: 137 amino acids
Theoretical weight: 15.06 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P36105 (Residues: 2-138; Coverage: 99%)
Gene names: RPL14A, YKL006W, YKL153
Sequence domains:
Large ribosomal subunit protein eL15A Chains: AQ, XQ
Molecule details ›
Chains: AQ, XQ
Length: 203 amino acids
Theoretical weight: 24.35 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05748 (Residues: 2-204; Coverage: 100%)
Gene names: RPL10A, RPL13A, RPL15A, YL10A, YLR029C
Sequence domains: Ribosomal L15
Large ribosomal subunit protein uL13A Chains: AU, XU
Molecule details ›
Chains: AU, XU
Length: 197 amino acids
Theoretical weight: 22.03 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P26784 (Residues: 3-199; Coverage: 99%)
Gene names: RPL13, RPL16A, RPL21A, YIL133C
Sequence domains: Ribosomal protein L13
Small ribosomal subunit protein uS2A Chains: P, Pb
Molecule details ›
Chains: P, Pb
Length: 206 amino acids
Theoretical weight: 22.81 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P32905 (Residues: 2-207; Coverage: 82%)
Gene names: NAB1, NAB1A, RPS0A, YGR214W, YST1
Sequence domains: Ribosomal protein S2
Small ribosomal subunit protein eS1A Chains: Q, Qb
Molecule details ›
Chains: Q, Qb
Length: 216 amino acids
Theoretical weight: 24.5 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P33442 (Residues: 20-235; Coverage: 85%)
Gene names: L9753.9, PLC1, RPS10A, RPS1A, YLR441C
Sequence domains: Ribosomal S3Ae family
Small ribosomal subunit protein uS5 Chains: R, Rb
Molecule details ›
Chains: R, Rb
Length: 217 amino acids
Theoretical weight: 23.21 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P25443 (Residues: 34-250; Coverage: 85%)
Gene names: G2893, RPS2, RPS4, SUP38, SUP44, YGL123W
Sequence domains:
Small ribosomal subunit protein uS3 Chains: A, Ab
Molecule details ›
Chains: A, Ab
Length: 223 amino acids
Theoretical weight: 24.7 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05750 (Residues: 3-225; Coverage: 93%)
Gene names: N1653, RPS3, SUF14, YNL178W
Sequence domains:
Small ribosomal subunit protein eS4A Chains: S, Sb
Molecule details ›
Chains: S, Sb
Length: 260 amino acids
Theoretical weight: 29.34 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX35 (Residues: 2-261; Coverage: 100%)
Gene names: J2186, RPS4A, RPS7B, YJR145C
Sequence domains:
Small ribosomal subunit protein uS7 Chains: B, Bb
Molecule details ›
Chains: B, Bb
Length: 206 amino acids
Theoretical weight: 22.91 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P26783 (Residues: 20-225; Coverage: 92%)
Gene names: J2045, RPS2, RPS5, YJR123W
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein eS6A Chains: T, Tb
Molecule details ›
Chains: T, Tb
Length: 218 amino acids
Theoretical weight: 24.97 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX37 (Residues: 1-218; Coverage: 92%)
Gene names: LPG18C, RPS101, RPS10B, RPS6A, YPL090C
Sequence domains: Ribosomal protein S6e
Small ribosomal subunit protein eS7A Chains: U, Ub
Molecule details ›
Chains: U, Ub
Length: 185 amino acids
Theoretical weight: 21.07 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P26786 (Residues: 3-187; Coverage: 97%)
Gene names: RPS30, RPS7A, YOR096W, YOR3177W
Sequence domains: Ribosomal protein S7e
Small ribosomal subunit protein eS8A Chains: V, Vb
Molecule details ›
Chains: V, Vb
Length: 200 amino acids
Theoretical weight: 22.54 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX39 (Residues: 1-200; Coverage: 100%)
Gene names: RPS14A, RPS8A, YBL06.05, YBL0613, YBL072C
Sequence domains: Ribosomal protein S8e
Small ribosomal subunit protein uS4A Chains: W, Wb
Molecule details ›
Chains: W, Wb
Length: 185 amino acids
Theoretical weight: 21.21 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: O13516 (Residues: 2-186; Coverage: 94%)
Gene names: RPS13A, RPS9A, YPL081W, YS11A
Sequence domains:
Small ribosomal subunit protein eS10A Chains: C, Cb
Molecule details ›
Chains: C, Cb
Length: 92 amino acids
Theoretical weight: 11.04 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q08745 (Residues: 1-92; Coverage: 88%)
Gene names: RPS10A, YOR293W
Sequence domains: Plectin/S10 domain
Small ribosomal subunit protein uS17A Chains: X, Xb
Molecule details ›
Chains: X, Xb
Length: 146 amino acids
Theoretical weight: 16.59 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX47 (Residues: 2-147; Coverage: 94%)
Gene names: RPS11A, RPS18A, YD9813.03, YDR025W
Sequence domains:
Small ribosomal subunit protein eS12 Chains: D, Db
Molecule details ›
Chains: D, Db
Length: 124 amino acids
Theoretical weight: 13.33 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P48589 (Residues: 20-143; Coverage: 87%)
Gene names: RPS12, YOR369C
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Small ribosomal subunit protein uS15 Chains: Y, Yb
Molecule details ›
Chains: Y, Yb
Length: 150 amino acids
Theoretical weight: 16.93 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05756 (Residues: 2-151; Coverage: 99%)
Gene names: D4252, RPS13, RPS13C, YD9609.18, YDR064W
Sequence domains:
Small ribosomal subunit protein uS11B Chains: Z, Zb
Molecule details ›
Chains: Z, Zb
Length: 128 amino acids
Theoretical weight: 13.56 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P39516 (Residues: 11-138; Coverage: 93%)
Gene names: CRY2, J0354, RPS14B, YJL191W
Sequence domains: Ribosomal protein S11
Small ribosomal subunit protein uS19 Chains: E, Eb
Molecule details ›
Chains: E, Eb
Length: 119 amino acids
Theoretical weight: 13.42 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q01855 (Residues: 14-132; Coverage: 84%)
Gene names: RPS15, RPS21, YOL040C
Sequence domains: Ribosomal protein S19
Small ribosomal subunit protein uS9A Chains: F, Fb
Molecule details ›
Chains: F, Fb
Length: 141 amino acids
Theoretical weight: 15.66 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX51 (Residues: 3-143; Coverage: 99%)
Gene names: RP61R, RPS16A, YM9375.12, YMR143W
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein eS17A Chains: G, Gb
Molecule details ›
Chains: G, Gb
Length: 125 amino acids
Theoretical weight: 14.27 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P02407 (Residues: 2-126; Coverage: 92%)
Gene names: RP51A, RPS17A, YML024W
Sequence domains: Ribosomal S17
Small ribosomal subunit protein uS13A Chains: H, Hb
Molecule details ›
Chains: H, Hb
Length: 145 amino acids
Theoretical weight: 16.94 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX55 (Residues: 2-146; Coverage: 99%)
Gene names: D9461.35, RPS18A, YDR450W
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein eS19A Chains: I, Ib
Molecule details ›
Chains: I, Ib
Length: 143 amino acids
Theoretical weight: 15.81 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P07280 (Residues: 2-144; Coverage: 99%)
Gene names: RP55A, RPS16AA, RPS19A, YOL121C
Sequence domains: Ribosomal protein S19e
Small ribosomal subunit protein uS10 Chains: J, Jb
Molecule details ›
Chains: J, Jb
Length: 101 amino acids
Theoretical weight: 11.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38701 (Residues: 19-119; Coverage: 84%)
Gene names: RPS20, URP2, YHL015W
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein eS21A Chains: a, ab
Molecule details ›
Chains: a, ab
Length: 87 amino acids
Theoretical weight: 9.76 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C0V8 (Residues: 1-87; Coverage: 100%)
Gene names: RPS21A, RPS25, RPS25A, RPS26A, YKR057W
Sequence domains: Ribosomal protein S21e
Small ribosomal subunit protein uS8A Chains: b, bb
Molecule details ›
Chains: b, bb
Length: 129 amino acids
Theoretical weight: 14.52 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C0W1 (Residues: 2-130; Coverage: 99%)
Gene names: J0355, RPS22A, RPS24, RPS24A, YJL190C
Sequence domains: Ribosomal protein S8
Small ribosomal subunit protein uS12A Chains: c, cb
Molecule details ›
Chains: c, cb
Length: 144 amino acids
Theoretical weight: 15.94 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX29 (Residues: 2-145; Coverage: 99%)
Gene names: G6178, RPS23A, RPS28A, YGR118W
Sequence domains: Ribosomal protein S12/S23
Small ribosomal subunit protein eS24A Chains: d, db
Molecule details ›
Chains: d, db
Length: 134 amino acids
Theoretical weight: 15.23 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX31 (Residues: 2-135; Coverage: 99%)
Gene names: RPS24A, RPS24EA, YER074W
Sequence domains: Ribosomal protein S24e
Small ribosomal subunit protein eS25A Chains: K, Kb
Molecule details ›
Chains: K, Kb
Length: 69 amino acids
Theoretical weight: 7.93 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q3E792 (Residues: 37-105; Coverage: 64%)
Gene names: RPS25A, RPS31A, YGR027C
Sequence domains: S25 ribosomal protein
Small ribosomal subunit protein eS26B Chains: e, eb
Molecule details ›
Chains: e, eb
Length: 97 amino acids
Theoretical weight: 11.02 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P39939 (Residues: 2-98; Coverage: 82%)
Gene names: RPS26B, YER131W
Sequence domains: Ribosomal protein S26e
Small ribosomal subunit protein eS27A Chains: f, fb
Molecule details ›
Chains: f, fb
Length: 81 amino acids
Theoretical weight: 8.76 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P35997 (Residues: 2-82; Coverage: 99%)
Gene names: RPS27A, YKL156W
Sequence domains: Ribosomal protein S27
Small ribosomal subunit protein eS28A Chains: L, Lb
Molecule details ›
Chains: L, Lb
Length: 63 amino acids
Theoretical weight: 7.12 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q3E7X9 (Residues: 5-67; Coverage: 94%)
Gene names: O3600, RPS28A, RPS33, RPS33A, YOR167C
Sequence domains: Ribosomal protein S28e
Small ribosomal subunit protein uS14A Chains: M, Mb
Molecule details ›
Chains: M, Mb
Length: 53 amino acids
Theoretical weight: 6.34 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P41057 (Residues: 4-56; Coverage: 95%)
Gene names: L8084.11, RPS29A, RPS36A, YLR388W, YS29A
Sequence domains: Ribosomal protein S14p/S29e
Small ribosomal subunit protein eS30A Chains: g, gb
Molecule details ›
Chains: g, gb
Length: 60 amino acids
Theoretical weight: 6.78 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX33 (Residues: 2-61; Coverage: 95%)
Gene names: L8003.23, RPS30A, YLR287BC, YLR287C-A
Sequence domains: Ribosomal protein S30
Small ribosomal subunit protein eS31 Chains: N, Nb
Molecule details ›
Chains: N, Nb
Length: 73 amino acids
Theoretical weight: 8.33 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05759 (Residues: 80-152; Coverage: 48%)
Gene names: L9470.14, RPS31, RPS37, UBI3, YLR167W
Sequence domains: Ribosomal protein S27a
Small ribosomal subunit protein RACK1 Chains: O, Ob
Molecule details ›
Chains: O, Ob
Length: 313 amino acids
Theoretical weight: 34.15 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38011 (Residues: 7-319; Coverage: 98%)
Gene names: ASC1, CPC2, YM9718.15C, YMR116C
Sequence domains: WD domain, G-beta repeat
Large ribosomal subunit protein uL22A Chains: AX, XX
Molecule details ›
Chains: AX, XX
Length: 184 amino acids
Theoretical weight: 20.59 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05740 (Residues: 1-184; Coverage: 100%)
Gene names: RPL17, RPL17A, RPL20A, YKL180W
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein eL18A Chains: BB, YB
Molecule details ›
Chains: BB, YB
Length: 185 amino acids
Theoretical weight: 20.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX49 (Residues: 2-186; Coverage: 100%)
Gene names: RP28A, RPL18A, YOL120C
Sequence domains: Ribosomal protein 60S L18 and 50S L18e
Large ribosomal subunit protein eL19A Chains: BF, YF
Molecule details ›
Chains: BF, YF
Length: 188 amino acids
Theoretical weight: 21.63 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX82 (Residues: 2-189; Coverage: 100%)
Gene names: RPL19A, RPL23A, YBR084BC, YBR084C-A, YL14A
Sequence domains: Ribosomal protein L19e
Large ribosomal subunit protein eL20A Chains: BH, YH
Molecule details ›
Chains: BH, YH
Length: 172 amino acids
Theoretical weight: 20.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX23 (Residues: 1-172; Coverage: 100%)
Gene names: RPL18A, RPL18A2, RPL20A, YM9408.04C, YMR242C
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
Large ribosomal subunit protein eL21A Chains: BJ, YJ
Molecule details ›
Chains: BJ, YJ
Length: 159 amino acids
Theoretical weight: 18.15 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q02753 (Residues: 2-160; Coverage: 99%)
Gene names: RPL21A, URP1, YBR1401, YBR191W
Sequence domains: Ribosomal protein L21e
Large ribosomal subunit protein eL22A Chains: BL, YL
Molecule details ›
Chains: BL, YL
Length: 98 amino acids
Theoretical weight: 11.01 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05749 (Residues: 11-108; Coverage: 81%)
Gene names: L2168, RPL22A, YLR061W
Sequence domains: Ribosomal L22e protein family
Large ribosomal subunit protein uL14A Chains: AB, XB
Molecule details ›
Chains: AB, XB
Length: 134 amino acids
Theoretical weight: 14.22 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX41 (Residues: 4-137; Coverage: 98%)
Gene names: RPL17A, RPL17AA, RPL23A, YBL0713, YBL087C
Sequence domains: Ribosomal protein L14p/L23e
Large ribosomal subunit protein eL24A Chains: AE, XE
Molecule details ›
Chains: AE, XE
Length: 135 amino acids
Theoretical weight: 15.51 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P04449 (Residues: 1-135; Coverage: 87%)
Gene names: RP29, RPL24A, RPL30A, YGL031C
Sequence domains: Ribosomal protein L24e
Large ribosomal subunit protein uL23 Chains: AH, XH
Molecule details ›
Chains: AH, XH
Length: 120 amino acids
Theoretical weight: 13.64 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P04456 (Residues: 23-142; Coverage: 85%)
Gene names: RPL25, YOL127W
Sequence domains:
Large ribosomal subunit protein uL24A Chains: AK, XK
Molecule details ›
Chains: AK, XK
Length: 124 amino acids
Theoretical weight: 13.89 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05743 (Residues: 2-125; Coverage: 98%)
Gene names: L8300.4, RPL26, RPL26A, RPL33A, YLR344W
Sequence domains:
Large ribosomal subunit protein eL27A Chains: AN, XN
Molecule details ›
Chains: AN, XN
Length: 135 amino acids
Theoretical weight: 15.44 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C2H6 (Residues: 2-136; Coverage: 99%)
Gene names: RPL27, RPL27A, YHR010W
Sequence domains: Ribosomal L27e protein family
Large ribosomal subunit protein uL15 Chains: AR, XR
Molecule details ›
Chains: AR, XR
Length: 148 amino acids
Theoretical weight: 16.63 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P02406 (Residues: 2-149; Coverage: 99%)
Gene names: CYH2, RPL28, YGL103W
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Large ribosomal subunit protein eL29 Chains: AV, XV
Molecule details ›
Chains: AV, XV
Length: 58 amino acids
Theoretical weight: 6.56 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05747 (Residues: 2-59; Coverage: 98%)
Gene names: RPL29, YFR032BW, YFR032C-A, YL43
Sequence domains: Ribosomal L29e protein family
Large ribosomal subunit protein eL30 Chains: AY, XY
Molecule details ›
Chains: AY, XY
Length: 100 amino acids
Theoretical weight: 10.9 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P14120 (Residues: 6-105; Coverage: 95%)
Gene names: RPL30, RPL32, YGL030W
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein eL31A Chains: BC, YC
Molecule details ›
Chains: BC, YC
Length: 109 amino acids
Theoretical weight: 12.65 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C2H8 (Residues: 4-112; Coverage: 97%)
Gene names: D2478, RPL31A, RPL34, RPL34A, YDL075W
Sequence domains: Ribosomal protein L31e
Large ribosomal subunit protein eL32 Chains: BG, YG
Molecule details ›
Chains: BG, YG
Length: 127 amino acids
Theoretical weight: 14.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38061 (Residues: 2-128; Coverage: 98%)
Gene names: RPL32, YBL0838, YBL092W
Sequence domains: Ribosomal protein L32
Large ribosomal subunit protein eL33A Chains: BK, YK
Molecule details ›
Chains: BK, YK
Length: 106 amino acids
Theoretical weight: 12.05 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05744 (Residues: 2-107; Coverage: 99%)
Gene names: LPI4W, P2625, RPL33A, RPL37A, YPL143W
Sequence domains: Ribosomal protein L35Ae
Large ribosomal subunit protein eL34A Chains: BN, YN
Molecule details ›
Chains: BN, YN
Length: 112 amino acids
Theoretical weight: 12.61 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P87262 (Residues: 2-113; Coverage: 93%)
Gene names: RPL34A, YER056BC, YER056C-A
Sequence domains: Ribosomal protein L34e
Large ribosomal subunit protein uL29A Chains: BP, YP
Molecule details ›
Chains: BP, YP
Length: 119 amino acids
Theoretical weight: 13.81 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX84 (Residues: 2-120; Coverage: 99%)
Gene names: D1249, RPL35A, SOS1, YDL191W
Sequence domains: Ribosomal L29 protein
Large ribosomal subunit protein eL36A Chains: AC, XC
Molecule details ›
Chains: AC, XC
Length: 99 amino acids
Theoretical weight: 11.02 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05745 (Residues: 2-100; Coverage: 99%)
Gene names: RPL36A, RPL39A, YM9646.06, YMR194W
Sequence domains: Ribosomal protein L36e
Large ribosomal subunit protein eL37A Chains: AF, XF
Molecule details ›
Chains: AF, XF
Length: 82 amino acids
Theoretical weight: 9.3 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P49166 (Residues: 2-83; Coverage: 93%)
Gene names: L9470.6, RPL35A, RPL37A, YLR185W
Sequence domains: Ribosomal protein L37e
Large ribosomal subunit protein eL38 Chains: AI, XI
Molecule details ›
Chains: AI, XI
Length: 77 amino acids
Theoretical weight: 8.71 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P49167 (Residues: 2-78; Coverage: 99%)
Gene names: L8543.2, RPL38, YLR325C
Sequence domains: Ribosomal L38e protein family
Large ribosomal subunit protein eL39 Chains: AL, XL
Molecule details ›
Chains: AL, XL
Length: 50 amino acids
Theoretical weight: 6.23 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P04650 (Residues: 2-51; Coverage: 98%)
Gene names: J0360, RPL39, RPL46, SPB2, YJL189W
Sequence domains: Ribosomal L39 protein
Large ribosomal subunit protein eL40A Chains: AO, XO
Molecule details ›
Chains: AO, XO
Length: 52 amino acids
Theoretical weight: 6.03 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CH08 (Residues: 77-128; Coverage: 41%)
Gene names: RPL40A, UBI1, YIL148W
Sequence domains: Ribosomal L40e family
Small ribosomal subunit protein eS32B Chains: AS, XS
Molecule details ›
Chains: AS, XS
Length: 25 amino acids
Theoretical weight: 3.35 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX87 (Residues: 1-25; Coverage: 100%)
Gene names: RPL41B, RPL47B, YDL133BC, YDL133C-A, YL41B
Sequence domains: Ribosomal protein L41
Large ribosomal subunit protein eL42A Chains: AP, XP
Molecule details ›
Chains: AP, XP
Length: 105 amino acids
Theoretical weight: 12.12 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX27 (Residues: 2-106; Coverage: 99%)
Gene names: N1722, RPL41A, RPL42A, SCL41A, YNL162W
Sequence domains: Ribosomal protein L44
Large ribosomal subunit protein eL43A Chains: AT, XT
Molecule details ›
Chains: AT, XT
Length: 91 amino acids
Theoretical weight: 9.98 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX25 (Residues: 2-92; Coverage: 99%)
Gene names: RPL43A, YP9499.02, YPR043W
Sequence domains: Ribosomal L37ae protein family
Large ribosomal subunit protein uL10 Chains: BU, YU
Molecule details ›
Chains: BU, YU
Length: 312 amino acids
Theoretical weight: 33.75 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05317 (Residues: 1-312; Coverage: 100%)
Gene names: L10E, L8300.8, RPA0, RPL10E, RPLA0, RPP0, YLR340W
Sequence domains:
25S ribosomal RNA Chains: BQ, YQ
Molecule details ›
Chains: BQ, YQ
Length: 3396 nucleotides
Theoretical weight: 1097.49 KDa
Sequence domains: Eukaryotic large subunit ribosomal RNA
5S ribosomal RNA Chains: BR, YR
Molecule details ›
Chains: BR, YR
Length: 121 nucleotides
Theoretical weight: 38.95 KDa
Sequence domains: 5S ribosomal RNA
5.8S ribosomal RNA Chains: BS, YS
Molecule details ›
Chains: BS, YS
Length: 157 nucleotides
Theoretical weight: 50.38 KDa
Sequence domains: 5.8S ribosomal RNA
18S Ribosomal RNA Chains: 2, 2b
Molecule details ›
Chains: 2, 2b
Length: 1800 nucleotides
Theoretical weight: 579.76 KDa
Sequence domains: Eukaryotic small subunit ribosomal RNA
P-site tRNA Chain: n
Molecule details ›
Chain: n
Length: 76 nucleotides
Theoretical weight: 24.47 KDa
E-site tRNA Chain: m
Molecule details ›
Chain: m
Length: 75 nucleotides
Theoretical weight: 24 KDa
A/P hybrid tRNA Chain: nb
Molecule details ›
Chain: nb
Length: 76 nucleotides
Theoretical weight: 24.5 KDa
Sequence domains: tRNA
P/E hybrid tRNA Chain: mb
Molecule details ›
Chain: mb
Length: 77 nucleotides
Theoretical weight: 24.8 KDa
Sequence domains: tRNA
Messenger RNA Chain: l
Molecule details ›
Chain: l
Length: 57 nucleotides
Theoretical weight: 17.9 KDa

Ligands and Environments

1 bound ligand:
Ligand ZN 15 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.3Å
Relevant EMDB volumes: EMD-4427

Quick links

Citations

31 review citations

Ribosomal stress-surveillance: three pathways is a magic number.
Vind et al. (2020)
30 more

6 mentions without citation

Measurement of atom resolvability in cryo-EM maps with Q-scores.
Pintilie et al. (2020)
5 more