› 6i9j

X-ray diffraction
2Å resolution

Human transforming growth factor beta2 in a tetragonal crystal form

Released:
DOI: 10.2210/pdb6i9j/pdb
PDB entry 6i9j coloured by chain, front view.
PDB entry 6i9j coloured by chain, side view.
PDB entry 6i9j coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor β2 in a new conformation.
Del Amo-Maestro L, Marino-Puertas L, Goulas T, Gomis-Rüth FX
Sci Rep 9 8660 (2019)
PMID: 31209258

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158384 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transforming growth factor beta-2 Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.73 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P61812 (Residues: 303-414; Coverage: 28%)
Gene name: TGFB2
Sequence domains: Transforming growth factor beta like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P41212
Unit cell:
a: 55.57Å b: 55.57Å c: 70.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.217 0.253
Expression system: Homo sapiens

Quick links

Citations

1 review citation

Regulation and Signaling of TGF-β Autoinduction.
Hariyanto et al. (2021)
2 other articles

2 mentions without citation

Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor β2 in a new conformation.
Del Amo-Maestro et al. (2019)
1 more