› 6ilg

X-ray diffraction
2.6Å resolution

CRYSTAL STRUCTURE OF BAT MHC CLASS I PTAL-N*01:01 FOR 2.6 ANGSTROM

Released:
DOI: 10.2210/pdb6ilg/pdb
PDB entry 6ilg coloured by chain, front view.
PDB entry 6ilg coloured by chain, side view.
PDB entry 6ilg coloured by chain, top view.
Source organism: Pteropus alecto
Primary publication:
Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding.
Qu Z, Li Z, Ma L, Wei X, Zhang L, Liang R, Meng G, Zhang N, Xia C
J Immunol 202 3493-3506 (2019)
PMID: 31076531

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-102856 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 32.35 KDa
Source organism: Pteropus alecto
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A125R585 (Residues: 25-303; Coverage: 81%)
Gene name: Ptal-N
Sequence domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 98 amino acids
Theoretical weight: 11.47 KDa
Source organism: Pteropus alecto
Expression system: Escherichia coli
UniProt:
  • Canonical: L5K3Y9 (Residues: 187-281; Coverage: 29%)
Gene name: PAL_GLEAN10023531
Sequence domains: Immunoglobulin C1-set domain
Phosphoprotein Chain: C
Molecule details ›
Chain: C
Length: 8 amino acids
Theoretical weight: 940 Da
UniProt:
  • Canonical: O55778 (Residues: 481-487; Coverage: 1%)
Gene name: P/V/C

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2221
Unit cell:
a: 72.876Å b: 86.44Å c: 135.121Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.214 0.276
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Novel Insights Into Immune Systems of Bats.
Banerjee et al. (2020)
3 more

1 mention without citation

Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding.
Qu et al. (2019)