› 6l6p

X-ray diffraction
3.08Å resolution

hASIC2a co-crystallized with Mamb-1

Released:
DOI: 10.2210/pdb6l6p/pdb
PDB entry 6l6p coloured by chain, front view.
PDB entry 6l6p coloured by chain, side view.
PDB entry 6l6p coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lei F, Jian S

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172468 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acid-sensing ion channel 2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 463 amino acids
Theoretical weight: 52.25 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q16515 (Residues: 13-461; Coverage: 88%)
Gene names: ACCN, ACCN1, ASIC2, BNAC1, MDEG
Sequence domains: Amiloride-sensitive sodium channel

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P212121
Unit cell:
a: 109.863Å b: 155.664Å c: 156.644Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.231 0.282
Expression system: Spodoptera frugiperda

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