› 6lj9

X-ray diffraction
2.31Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143190 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SUMO-1 cysteine protease S273R Chains: A, B
Molecule details ›
Chains: A, B
Length: 281 amino acids
Theoretical weight: 32.92 KDa
Source organism: African swine fever virus pig/Kenya/KEN-50/1950
Expression system: Escherichia coli
UniProt:
  • Canonical: P0C9B9 (Residues: 1-273; Coverage: 100%)
Gene name: Ken-123
Sequence domains: Ulp1 protease family, C-terminal catalytic domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 60.165Å b: 83.28Å c: 108.724Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.191 0.22
Expression system: Escherichia coli

Quick links

Citations

6 review citations

African Swine Fever Virus: A Review.
Li et al. (2022)
5 more

2 mentions without citation

Crystal Structure of African Swine Fever Virus pS273R Protease and Implications for Inhibitor Design.
Li et al. (2020)
1 more