6m86

X-ray diffraction
3.6Å resolution

Crystal Structure of Inward Rectifier Kir2.2 Force Open Mutant

Released:
Source organism: Gallus gallus
Entry authors: Lee S-J, Ren F, Yuan P, Nichols CG

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-123320 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-sensitive inward rectifier potassium channel 12 Chain: A
Molecule details ›
Chain: A
Length: 343 amino acids
Theoretical weight: 39.48 KDa
Source organism: Gallus gallus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: F1NHE9 (Residues: 38-366; Coverage: 77%)
Gene name: KCNJ12
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: I4
Unit cell:
a: 82.852Å b: 82.852Å c: 189.109Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.234 0.287
Expression system: Komagataella pastoris