Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- SH2 domain
- SH2 domain superfamily
- STAT transcription factor, DNA-binding
- STAT transcription factor, DNA-binding, N-terminal
- STAT5a/5b, DNA-binding domain
- p53-like transcription factor, DNA-binding domain superfamily
- STAT transcription factor, all-alpha domain
- STAT5a/5b, coiled-coil domain
2 more domains
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156406 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Signal transducer and activator of transcription 5B
Molecule details ›
Chains: A, B
Length: 572 amino acids
Theoretical weight: 65.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 572 amino acids
Theoretical weight: 65.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P51692 (Residues: 136-703; Coverage: 72%)
Sequence domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-E
Spacegroup:
P21212
Expression system: Escherichia coli BL21(DE3)
