› 6mpn

X-ray diffraction
1.4Å resolution

Racemic M2-TM I42E crystallized from racemic detergent

Released:
DOI: 10.2210/pdb6mpn/pdb
PDB entry 6mpn coloured by chain, front view.
PDB entry 6mpn coloured by chain, side view.
PDB entry 6mpn coloured by chain, top view.
Source organism: Influenza A virus (A/Hong Kong/156/97(H5N1))
Primary publication:
A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
Kreitler DF, Yao Z, Steinkruger JD, Mortenson DE, Huang L, Mittal R, Travis BR, Forest KT, Gellman SH
J Am Chem Soc 141 1583-1592 (2019)
PMID: 30645104

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130716 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Matrix protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 24 amino acids
Theoretical weight: 2.5 KDa
Source organism: Influenza A virus (A/Hong Kong/156/97(H5N1))
Expression system: Not provided
UniProt:
  • Canonical: O70632 (Residues: 25-46; Coverage: 23%)
Gene name: M

Ligands and Environments

1 bound ligand:
Ligand BOG 2 x BOG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Unit cell:
a: 14.68Å b: 37.25Å c: 43.22Å
α: 107.41° β: 96.73° γ: 97.66°
R-values:
R R work R free
0.231 0.23 0.237
Expression system: Not provided

Quick links

Citations

2 review citations

Peptide-based supramolecular vaccine systems.
O'Neill et al. (2021)
1 more

1 mention without citation

A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
Kreitler et al. (2019)