6mzc

Electron Microscopy
4.5Å resolution

Human TFIID BC core

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-126217 (preferred)
Entry contents:
10 distinct polypeptide molecules
Macromolecules (10 distinct):
Transcription initiation factor TFIID subunit 2 Chain: B
Molecule details ›
Chain: B
Length: 1199 amino acids
Theoretical weight: 137.16 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q6P1X5 (Residues: 1-1199; Coverage: 100%)
Gene names: CIF150, TAF2, TAF2B
Transcription initiation factor TFIID subunit 4 Chain: E
Molecule details ›
Chain: E
Length: 1085 amino acids
Theoretical weight: 110.22 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O00268 (Residues: 1-1085; Coverage: 100%)
Gene names: TAF2C, TAF2C1, TAF4, TAF4A, TAFII130, TAFII135
Sequence domains:
Transcription initiation factor TFIID subunit 5 Chain: G
Molecule details ›
Chain: G
Length: 800 amino acids
Theoretical weight: 85.79 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q15542 (Residues: 1-800; Coverage: 100%)
Gene names: TAF2D, TAF5
Sequence domains:
Transcription initiation factor TFIID subunit 6 Chain: H
Molecule details ›
Chain: H
Length: 677 amino acids
Theoretical weight: 72.75 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P49848 (Residues: 1-677; Coverage: 100%)
Gene names: TAF2E, TAF6, TAFII70
Sequence domains:
Transcription initiation factor TFIID subunit 6 Chain: I
Molecule details ›
Chain: I
Length: 677 amino acids
Theoretical weight: 72.37 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P49848 (Residues: 1-677; Coverage: 100%)
Gene names: TAF2E, TAF6, TAFII70
Sequence domains:
Transcription initiation factor TFIID subunit 8 Chain: K
Molecule details ›
Chain: K
Length: 310 amino acids
Theoretical weight: 32.98 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q7Z7C8 (Residues: 1-310; Coverage: 100%)
Gene names: TAF8, TAFII43, TBN
Sequence domains:
Transcription initiation factor TFIID subunit 9 Chain: M
Molecule details ›
Chain: M
Length: 264 amino acids
Theoretical weight: 28.83 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q16594 (Residues: 1-264; Coverage: 100%)
Gene names: TAF2G, TAF9, TAFII31
Sequence domains: Transcription initiation factor IID, 31kD subunit
Transcription initiation factor TFIID subunit 10 Chain: O
Molecule details ›
Chain: O
Length: 218 amino acids
Theoretical weight: 21.73 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q12962 (Residues: 1-218; Coverage: 100%)
Gene names: TAF10, TAF2A, TAF2H, TAFII30
Sequence domains: Transcription initiation factor TFIID 23-30kDa subunit
Transcription initiation factor TFIID subunit 12 Chain: R
Molecule details ›
Chain: R
Length: 161 amino acids
Theoretical weight: 17.95 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q16514 (Residues: 1-161; Coverage: 100%)
Gene names: TAF12, TAF15, TAF2J, TAFII20
Sequence domains: Transcription initiation factor TFIID subunit A
poly(UNK) Chain: Z
Molecule details ›
Chain: Z
Length: 238 amino acids
Theoretical weight: 20.27 KDa
Source organism: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.5Å
Relevant EMDB volumes: EMD-9298