› 6ng9

X-ray diffraction
1.95Å resolution

Crystal structure of human CD160

Released:
DOI: 10.2210/pdb6ng9/pdb
PDB entry 6ng9 coloured by chain, front view.
PDB entry 6ng9 coloured by chain, side view.
PDB entry 6ng9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural Basis of CD160:HVEM Recognition.
Liu W, Garrett SC, Fedorov EV, Ramagopal UA, Garforth SJ, Bonanno JB, Almo SC
Structure 27 1286-1295.e4 (2019)
PMID: 31230945

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132093 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD160 antigen, soluble form Chains: A, B
Molecule details ›
Chains: A, B
Length: 119 amino acids
Theoretical weight: 13.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpB1GAP_S
UniProt:
  • Canonical: O95971 (Residues: 27-144; Coverage: 75%)
Gene names: BY55, CD160

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 44.572Å b: 51.436Å c: 95.426Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.202 0.253
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpB1GAP_S

Quick links

Citations

6 review citations

Targeting the ubiquitination/deubiquitination process to regulate immune checkpoint pathways.
Liu et al. (2021)
5 more

2 mentions without citation

Structural Basis of CD160:HVEM Recognition.
Liu et al. (2019)
1 more