Function and Biology Details
Reaction catalysed:
Cytosine in single-stranded DNA + H(2)O = uracil in single-stranded DNA + NH(3)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-146246 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
DNA dC->dU-editing enzyme APOBEC-3F
Molecule details ›
Chains: A, D, G, J
Length: 207 amino acids
Theoretical weight: 24.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: APOBEC-like N-terminal domain
Length: 207 amino acids
Theoretical weight: 24.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8IUX4 (Residues: 185-373; Coverage: 51%)
Sequence domains: APOBEC-like N-terminal domain
Core-binding factor subunit beta
Molecule details ›
Chains: B, E, H, K
Length: 151 amino acids
Theoretical weight: 17.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Core binding factor beta subunit
Length: 151 amino acids
Theoretical weight: 17.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q13951 (Residues: 1-151; Coverage: 83%)
Sequence domains: Core binding factor beta subunit
Virion infectivity factor
Molecule details ›
Chains: C, F, I, L
Length: 138 amino acids
Theoretical weight: 16.74 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
Sequence domains: Retroviral Vif (Viral infectivity) protein
Length: 138 amino acids
Theoretical weight: 16.74 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
- Canonical: P12504 (Residues: 1-113, 158-176; Coverage: 69%)
Sequence domains: Retroviral Vif (Viral infectivity) protein
