› 6o3n

X-ray diffraction
3.7Å resolution

Cross-alpha Amyloid-like Structure alphaAmA

Released:
DOI: 10.2210/pdb6o3n/pdb
PDB entry 6o3n coloured by chain, front view.
PDB entry 6o3n coloured by chain, side view.
PDB entry 6o3n coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Designed peptides that assemble into cross-α amyloid-like structures.
Zhang SQ, Huang H, Yang J, Kratochvil HT, Lolicato M, Liu Y, Shu X, Liu L, DeGrado WF
Nat Chem Biol 14 870-875 (2018)
PMID: 30061717

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo 32-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167181 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cross-alpha Amyloid-like Structure alphaAmA Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Length: 27 amino acids
Theoretical weight: 2.93 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: I4122
Unit cell:
a: 164.816Å b: 164.816Å c: 164.134Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.299 0.297 0.319
Expression system: Not provided

Quick links

Citations

5 review citations

De novo protein design, a retrospective.
Korendovych et al. (2020)
4 more