Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero nonadecamer (preferred)
PDBe Complex ID:
PDB-CPX-112589 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
UL19
Molecule details ›
Chains: S, T, W, X
Length: 1374 amino acids
Theoretical weight: 149.3 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
Sequence domains: Herpes virus major capsid protein
Length: 1374 amino acids
Theoretical weight: 149.3 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
- Canonical:
H9E925 (Residues: 1-1374; Coverage: 100%)
Sequence domains: Herpes virus major capsid protein
Small capsomere-interacting protein
Molecule details ›
Chains: E, F, L, P
Length: 112 amino acids
Theoretical weight: 12.11 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
Sequence domains: Herpesvirus UL35 family
Length: 112 amino acids
Theoretical weight: 12.11 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
- Canonical: Q25BW6 (Residues: 1-112; Coverage: 100%)
Sequence domains: Herpesvirus UL35 family
UL38
Molecule details ›
Chains: 5, D
Length: 465 amino acids
Theoretical weight: 50.37 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
Sequence domains: Herpesvirus capsid shell protein VP19C
Length: 465 amino acids
Theoretical weight: 50.37 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
- Canonical: Q1T724 (Residues: 1-465; Coverage: 100%)
Sequence domains: Herpesvirus capsid shell protein VP19C
Capsid triplex subunit 2
Molecule details ›
Chains: 6, 7, A, H
Length: 318 amino acids
Theoretical weight: 34.3 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
Sequence domains: Herpesvirus VP23 like capsid protein
Length: 318 amino acids
Theoretical weight: 34.3 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
- Canonical: G8H8D9 (Residues: 1-318; Coverage: 100%)
Sequence domains: Herpesvirus VP23 like capsid protein
UL17
Molecule details ›
Chain: C
Length: 703 amino acids
Theoretical weight: 74.77 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
Sequence domains: Herpesvirus UL17 protein
Length: 703 amino acids
Theoretical weight: 74.77 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
- Canonical: F8REV0 (Residues: 1-703; Coverage: 100%)
Sequence domains: Herpesvirus UL17 protein
DNA packaging tegument protein
Molecule details ›
Chains: G, K
Length: 580 amino acids
Theoretical weight: 62.75 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
Sequence domains: Herpesvirus UL25 family
Length: 580 amino acids
Theoretical weight: 62.75 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
- Canonical: D3YPI2 (Residues: 1-580; Coverage: 100%)
Sequence domains: Herpesvirus UL25 family
Peptidase C76 domain-containing protein
Molecule details ›
Chains: B, O
Length: 3094 amino acids
Theoretical weight: 329.18 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
Sequence domains:
Length: 3094 amino acids
Theoretical weight: 329.18 KDa
Source organism: Human alphaherpesvirus 1 strain KOS
UniProt:
- Canonical: I1UYK0 (Residues: 1-3108; Coverage: 100%)
Sequence domains:
