PDB 6ot1 structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Biochemical function:

structural molecule activity

Biological process:

not assigned

Cellular component:

viral envelope

Sequence domains:

5 more domains

Structure analysis Details

Assembly composition:

hetero 24-mer (preferred)

Assembly name:

Envelope glycoprotein gp160 and IG-heavy chain and IG-light kappa chain and IG-heavy chain and IG-light lambda chain and IG-heavy chain and IG-light k... (preferred)
show full assembly name

PDBe Complex ID:

PDB-CPX-212157 (preferred)

Entry contents:

8 distinct polypeptide molecules

Macromolecules (13 distinct):

Transmembrane protein gp41 Chains: B, D, O

Molecule details ›

Chains: B, D, O
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:

Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)

Gene name: env
Sequence domains: Retroviral envelope protein

Envelope glycoprotein gp160 Chains: E, G, P

Molecule details ›

Chains: E, G, P
Length: 480 amino acids
Theoretical weight: 53.99 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:

Canonical: Q2N0S6 (Residues: 30-508; Coverage: 56%)

Gene name: env
Sequence domains: Envelope glycoprotein GP120

0PV-b.01 heavy Chains: A, H, M

0PV-b.01 light Chains: C, L, N

PGT122 heavy Chains: F, Q, m

PGT122 light Chains: I, R, n

VRC03 heavy Chains: J, S, q

VRC03 light Chains: K, T, r

Ligands and Environments

Carbohydrate polymer : NEW

1 bound ligand:

No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.

Resolution: 3.5Å

Relevant EMDB volumes: EMD-20191

Expression system: Homo sapiens

Protein Data Bank in Europe

Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122

Function and Biology Details

Structure analysis Details

Ligands and Environments

Experiments and Validation Details

Quick links

Citations

10 review citations

4 mentions without citation

PDBe › 6ot1

Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122

Function and Biology Details

Structure analysis Details

Ligands and Environments

Experiments and Validation Details

Quick links

Citations

10 review citations

4 mentions without citation