Protein Data Bank in Europe

Chains: A, E
Length: 135 amino acids
Theoretical weight: 15.3 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:

• Canonical: P84233 (Residues: 2-136; Coverage: 99%)

Sequence domains: Core histone H2A/H2B/H3/H4

Chains: B, F
Length: 103 amino acids
Theoretical weight: 11.39 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:

• Canonical: P62799 (Residues: 1-103; Coverage: 100%)

Sequence domains: Centromere kinetochore component CENP-T histone fold

Chains: C, G
Length: 129 amino acids
Theoretical weight: 13.98 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:

• Canonical: P06897 (Residues: 2-130; Coverage: 99%)

Sequence domains:

• Core histone H2A/H2B/H3/H4
• C-terminus of histone H2A

Chains: D, H
Length: 123 amino acids
Theoretical weight: 13.66 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:

• Canonical: P02281 (Residues: 5-126; Coverage: 97%)

Sequence domains: Core histone H2A/H2B/H3/H4

Chains: K, P
Length: 689 amino acids
Theoretical weight: 77.91 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q9Y6K1 (Residues: 224-912; Coverage: 76%)

Gene name: DNMT3A
Sequence domains:

• PWWP domain
• Cysteine rich ADD domain in DNMT3
• DNMT3, ADD PHD zinc finger
• C-5 cytosine-specific DNA methylase

Chains: N, S
Length: 770 amino acids
Theoretical weight: 86.29 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q9UBC3 (Residues: 1-853; Coverage: 90%)

Gene name: DNMT3B
Sequence domains:

• PWWP domain
• Cysteine rich ADD domain in DNMT3
• DNMT3, ADD PHD zinc finger
• C-5 cytosine-specific DNA methylase

Chain: I
Length: 167 nucleotides
Theoretical weight: 51.33 KDa

Chain: J
Length: 167 nucleotides
Theoretical weight: 51.79 KDa