Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- RNA recognition motif domain
- WD40/YVTN repeat-like-containing domain superfamily
- DDB1- and CUL4-associated factor 15, WD40 repeat-containing domain
- DET1- and DDB1-associated protein 1 domain
- DET1- and DDB1-associated protein 1-like
- RNA-binding domain superfamily
- Splicing factor, RBM39-like
- Nucleotide-binding alpha-beta plait domain superfamily
5 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-172016 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
DNA damage-binding protein 1
Molecule details ›
Chain: A
Length: 1140 amino acids
Theoretical weight: 127.1 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 1140 amino acids
Theoretical weight: 127.1 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q16531 (Residues: 1-1140; Coverage: 100%)
Sequence domains:
DDB1- and CUL4-associated factor 15
Molecule details ›
Chain: C
Length: 498 amino acids
Theoretical weight: 56.41 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: DDB1-and CUL4-substrate receptor 15, WD repeat
Length: 498 amino acids
Theoretical weight: 56.41 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q66K64 (Residues: 2-600; Coverage: 82%)
Sequence domains: DDB1-and CUL4-substrate receptor 15, WD repeat
RNA-binding protein 39
Molecule details ›
Chain: D
Length: 109 amino acids
Theoretical weight: 12.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: RNA recognition motif
Length: 109 amino acids
Theoretical weight: 12.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q14498 (Residues: 235-331; Coverage: 18%)
Sequence domains: RNA recognition motif
DET1- and DDB1-associated protein 1
Molecule details ›
Chain: E
Length: 102 amino acids
Theoretical weight: 11.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Det1 complexing ubiquitin ligase
Length: 102 amino acids
Theoretical weight: 11.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q9BW61 (Residues: 1-102; Coverage: 100%)
Sequence domains: Det1 complexing ubiquitin ligase
