› 6q3m

X-ray diffraction
2.52Å resolution

Structure of CHD4 PHD2 - tandem chromodomains

Released:
DOI: 10.2210/pdb6q3m/pdb
PDB entry 6q3m coloured by chain, front view.
PDB entry 6q3m coloured by chain, side view.
PDB entry 6q3m coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Alt A, Mancini EJ

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172109 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromodomain-helicase-DNA-binding protein 4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 238 amino acids
Theoretical weight: 28.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14839 (Residues: 444-679; Coverage: 12%)
Gene name: CHD4
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand ZN 8 x ZN
Ligand PGE 5 x PGE
Ligand EDO 22 x EDO
Ligand PEG 2 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 70.731Å b: 87.681Å c: 129.257Å
α: 90° β: 93.57° γ: 90°
R-values:
R R work R free
0.232 0.23 0.263
Expression system: Escherichia coli

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