› 6qe4

X-ray diffraction
2.3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178301 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative transferase CAF17, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 34.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5T440 (Residues: 31-356; Coverage: 92%)
Gene names: C1orf69, IBA57

Ligands and Environments

1 bound ligand:
Ligand I3C 4 x I3C
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCE ULTRA
Spacegroup: P1
Unit cell:
a: 38.111Å b: 43.048Å c: 59.281Å
α: 77.92° β: 75.63° γ: 71.67°
R-values:
R R work R free
0.208 0.206 0.228
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Multiple Mitochondrial Dysfunction Syndrome Type 3: A Likely Pathogenic Homozygous Variant Affecting a Patient of Cuban Descent and Literature Review.
Lang et al. (2022)
1 other article

2 mentions without citation

Molecular Basis of Rare Diseases Associated to the Maturation of Mitochondrial [4Fe-4S]-Containing Proteins.
Camponeschi et al. (2022)
1 more