6qnu

Electron Microscopy
3.8Å resolution

Human Adenovirus type 3 fiber knob in complex with two copies of Desmoglein-2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-137881 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fiber protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 189 amino acids
Theoretical weight: 21.03 KDa
Source organism: Human adenovirus B3
Expression system: Escherichia coli
UniProt:
  • Canonical: P04501 (Residues: 130-318; Coverage: 59%)
Gene name: L5
Sequence domains: Adenoviral fibre protein (knob domain)
Structure domains: Adenovirus pIV-related, attachment domain
Desmoglein-2 Chains: D, E
Molecule details ›
Chains: D, E
Length: 224 amino acids
Theoretical weight: 25.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14126 (Residues: 157-380; Coverage: 21%)
Gene names: CDHF5, DSG2
Sequence domains: Cadherin domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-4609
Expression system: Escherichia coli