› 6ra7

X-ray diffraction
1.2Å resolution

Human tnik in complex with compound 9

Released:
DOI: 10.2210/pdb6ra7/pdb
PDB entry 6ra7 coloured by chain, front view.
PDB entry 6ra7 coloured by chain, side view.
PDB entry 6ra7 coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Read JA

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193843 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TRAF2 and NCK-interacting protein kinase Chain: A
Molecule details ›
Chain: A
Length: 306 amino acids
Theoretical weight: 35.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UKE5 (Residues: 11-314; Coverage: 22%)
Gene names: KIAA0551, TNIK
Sequence domains: Protein kinase domain

Ligands and Environments

3 bound ligands:
Ligand EDO 1 x EDO
Ligand MG 1 x MG
Ligand JWK 1 x JWK
1 modified residue:
Ligand TPO 2 x TPO

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 48.916Å b: 53.667Å c: 127.927Å
α: 90° β: 90° γ: 90°
Expression system: Escherichia coli

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