› 6s8x

X-ray diffraction
2.29Å resolution

Crystal structure of the Rab-binding domain of FIP2

Released:
DOI: 10.2210/pdb6s8x/pdb
PDB entry 6s8x coloured by chain, front view.
PDB entry 6s8x coloured by chain, side view.
PDB entry 6s8x coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the Rab-binding domain of Rab11 family-interacting protein 2.
Kearney AM, Khan AR
Acta Crystallogr F Struct Biol Commun 76 357-363 (2020)
PMID: 32744247

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181636 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rab11 family-interacting protein 2 Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 78 amino acids
Theoretical weight: 9.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli #1/H766
UniProt:
  • Canonical: Q7L804 (Residues: 439-512; Coverage: 15%)
Gene names: KIAA0941, RAB11FIP2
Sequence domains: FIP domain

Ligands and Environments

1 bound ligand:
Ligand HEZ 1 x HEZ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2221
Unit cell:
a: 62.538Å b: 68.43Å c: 172.086Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.247 0.246 0.274
Expression system: Escherichia coli #1/H766

Quick links

Citations

1 citations in other articles

RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells.
Joseph et al. (2023)

1 mention without citation

Crystal structure of the Rab-binding domain of Rab11 family-interacting protein 2.
Kearney et al. (2020)