› 6sl9

X-ray diffraction
1.27Å resolution

High resolution apo structure of isomerase PaaG

Released:
DOI: 10.2210/pdb6sl9/pdb
PDB entry 6sl9 coloured by chain, front view.
PDB entry 6sl9 coloured by chain, side view.
PDB entry 6sl9 coloured by chain, top view.
Source organism: Thermus thermophilus JL-18
Primary publication:
Structural and Mechanistic Basis of an Oxepin-CoA Forming Isomerase in Bacterial Primary and Secondary Metabolism.
Spieker M, Saleem-Batcha R, Teufel R
ACS Chem Biol 14 2876-2886 (2019)
PMID: 31689071

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124979 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enoyl-CoA hydratase/carnithine racemase Chain: AAA
Molecule details ›
Chain: AAA
Length: 258 amino acids
Theoretical weight: 27.95 KDa
Source organism: Thermus thermophilus JL-18
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: H9ZNW0 (Residues: 1-254; Coverage: 100%)
Gene name: TtJL18_0099
Sequence domains: Enoyl-CoA hydratase/isomerase

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P213
Unit cell:
a: 88.497Å b: 88.497Å c: 88.497Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.147 0.146 0.179
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Progress in structural and functional study of the bacterial phenylacetic acid catabolic pathway, its role in pathogenicity and antibiotic resistance.
Jiao et al. (2022)
4 other articles

1 mention without citation

Bacterial Tropone Natural Products and Derivatives: Overview of their Biosynthesis, Bioactivities, Ecological Role and Biotechnological Potential.
Duan et al. (2020)