Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-136224 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Transferrin receptor subunit ESAG6
Molecule details ›
Chain: A
Length: 399 amino acids
Theoretical weight: 43.9 KDa
Source organism: Trypanosoma brucei
Expression system: Cricetulus longicaudatus
UniProt:
Sequence domains: Trypanosome variant surface glycoprotein (A-type)
Length: 399 amino acids
Theoretical weight: 43.9 KDa
Source organism: Trypanosoma brucei
Expression system: Cricetulus longicaudatus
UniProt:
- Canonical:
Q8WPU1 (Residues: 1-399; Coverage: 100%)
Sequence domains: Trypanosome variant surface glycoprotein (A-type)
Transferrin receptor subunit ESAG7
Molecule details ›
Chain: B
Length: 338 amino acids
Theoretical weight: 37.67 KDa
Source organism: Trypanosoma brucei
Expression system: Cricetulus longicaudatus
UniProt:
Sequence domains: Trypanosome variant surface glycoprotein (A-type)
Length: 338 amino acids
Theoretical weight: 37.67 KDa
Source organism: Trypanosoma brucei
Expression system: Cricetulus longicaudatus
UniProt:
- Canonical: Q8WPU2 (Residues: 1-338; Coverage: 100%)
Sequence domains: Trypanosome variant surface glycoprotein (A-type)
Serotransferrin
Molecule details ›
Chain: C
Length: 677 amino acids
Theoretical weight: 75.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Transferrin
Length: 677 amino acids
Theoretical weight: 75.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P02787 (Residues: 22-698; Coverage: 100%)
Sequence domains: Transferrin
Ligands and Environments
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I03
Spacegroup:
C2
Expression systems:
- Cricetulus longicaudatus
- Homo sapiens
